Title: 2711 - Oral Fluid Biomaterial for Screening Communicable Diseases in Africa
Agnes Gatarayiha (Presenter)
University of Rwanda
Objectives: We will present the utility of saliva as a biomaterial for detecting various communicable and non-communicable diseases in Africa
We will show the importance of salivary biomakers in reduction of blood transmission diseases in Africa
Methods: Whole saliva, collected from the patients with various communicable and non-communicable diseases, will be used to evaluate the biomarkers for early detection. it is a prospective case control study and ELISA technique will be also used to analyze the saliva
Results: It has been found from recent studies that some biomarkers appear in saliva much earlier than in blood. For instance, a significant elevation of salivary phosphate content was associated with the evolvement of childhood obesity, while no such changes in phosphate levels were noted in plasma among the same group of children. It has also been shown that saliva used as quick, easy and reliable method for detecting the microbial and production of inflammatory cytokines, including interleukin-1a and 1b in patients with periodontal diseases.
Conclusions: We highlight the importance of adopting salivary biomarkers as a part of patient screening system to reduce burden on blood-based laboratory analysis, and more importantly reduce the risk of blood-related disease transmission, and to make it more cost-effective in African countries including Rwanda.
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: I will need a financial support if my abstract has been accepted