Title: 2641 - Relationship Between Periodontal Health and Periodontopathogens in the Subglottic Area
Carlos Rubio Morillo (Presenter)
University of Sao paulo
Luciana Saraiva, University of Sao paulo
Maria Carmona, Medical School of University of São Paulo
Giuseppe Romito, University of Sao paulo
Cristina Villar, University of Texas at San Antonio
Objectives: The objective of this study was to evaluate the impact of the periodontal health status and oral care with chlorhexidine (CHX) on the presence of periodontopathogenic microorganisms in subglottic samples of mechanically ventilated patients.
Methods: 43 patients scheduled for elective surgery under general anesthesia with tracheal intubation were included. A full-mouth periodontal exam was conducted prior to the surgery. Three chronic periodontitis criteria were evaluated. On the day of surgery, patients were randomized into two groups that rinsed with CHX 0.12% or saline solution for 30 seconds. After 3h of tracheal intubation, the contents of the subglottic region were aspirated and stored. Quantification of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), and Tannerella forsythia (Tf) were assessed by real-time PCR.
Results: Patients with Pg in the subglottic samples had significantly higher plaque index (p<0.05). There were no significant differences in Pg, Tf and Aa counts in patients with CP in comparison with periodontally healthy subjects, irrespective of the case definition (p>0.05). Likewise, none of the single periodontal parameters evaluated (i.e. clinical probing depth, bleeding on probing, clinical attachment level) had an impact on subglottic Pg, Tf and Aa counts (p>0.05). Finally, oral rinse with 0.12% CHX failed to reduce Pg, Tf and Aa counts on subglottic samples
Conclusions: In mechanically ventilated patients, dental plaque accumulation may result in higher colonization of the upper respiratory tract by periodontal pathogens. In these patients, a single oral rinse with CHX 0.12% failed to reduce the bacterial load on subglottic samples.
This abstract is based on research that was funded entirely or partially by an outside source:
Latino American Oral Health Association
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: NONE