Title: 2100 - Analysis of Non-Caries Cervical Lesion Restorative Material: An OHTA report
Murali Ramamoorthi (Presenter)
Paula Bailsi, Mcgill University
Aparna Narvekar, Mcgill University
Zi Xuan Yin, Mcgill University
HoeJoong Yang, Mcgill University
Shahrokh Esfandiari, Mcgill University
Objectives: The primary objective is to systematically review and analyze existing evidence of clinical and cost effectiveness of restorative material that are deemed most suitable for Non-Caries Cervical Lesion (NCCL). .
Methods: A Health Technology Assessment methodology was applied. The protocol has been registered (registration number CRD4201603768) in the International Prospective Register of Systematic Reviews. Literature search was conducted in 14 databases. Among the selected studies, relevant data were extracted using priori inclusion criteria and critical appraisal was conducted accordingly. Summary estimates of the annual survival, failure, and event-free proportions and odd ratio (OR) were obtained using a random effects model with a 95% confidence interval. A Markov model simulated the lifetime of a patient and a decision tree over 15 years was developed to estimate the cost effectiveness.
Results: 565 abstracts and 173 full text articles were screened among which 34 were included for final review. These studies enrolled a total of 2955 patients with 9160 restorations and evaluated five major classes of direct tooth color restorative materials. Network meta-analysis of 29 different studies with total of 7109 restorations confirmed that Resin Modified Glass Ionomer (RMGIC) restorations has the lower risk of failure, while flowable composite-resin restorations has the highest risk of failure in non-carious cervical lesions. Among the 11 different restorative material evaluated for cost effectiveness, RMGIC restorations emerged as the best cost effective material followed by Nanoceramic composite-resin restorations.
Conclusions: The results suggest that resin modified glass ionomer cement is the most appropriate Class V restorative material in non-carious cervical lesions based on its clinical and cost effectiveness. This study highlights the value of Oral Health Technology Assessment to facilitate meaningful clinical decision-making in choosing suitable restorative material for class V non-carious cervical lesion.
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None