posterpresentation
Description

Title: 0808 - Anticaries Effect of Fluoride Varnish Containing Sodium Trimetaphosphate in Children

Authors:

CAIO SAMPAIO (Presenter)
School of Dentistry, Araçatuba, São Paulo State University (UNESP)

Alberto Delbem, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Michele Manarelli, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Douglas Monteiro, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Liliana Carolina Báez Quintero, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Heitor Honório, Bauru School of Dentistry, University of São Paulo
Juliano Pessan, School of Dentistry, Araçatuba, São Paulo State University (UNESP)

Abstract:

Objectives: This study assessed the clinical effectiveness of a fluoride varnish supplemented with sodium trimetaphosphate (TMP) on the development of caries lesions in the primary dentition, in a randomized, double-blind and controlled clinical trial.

Methods: The study population comprised children (n=390, 3-4 years old) attending public kindergartens in the city of Boa Vista, northern region of Brazil. Participants were randomly assigned into 3 treatment groups, according to the varnishes to be used: NaF 5% (F-varnish), NaF 5% + TMP 5% (F/TMP-varnish) and placebo (PLA, no fluoride or TMP). Randomization considered age, gender and baseline dmfs (decayed, missing, or filled surfaces). Fluoride dentifrices (1100 ppm F, as NaF) and toothbrushes were provided to all children and their families every three months, along with instructions regarding brushing frequency (twice/day) and amount of dentifrice (smear) used during toothbrushing. Children were examined at kindergartens by a single calibrated dentist, at the beginning of the study and every 3 months (for up to 12 months), by visual inspection using a plane mirror and a ballpoint probe. Varnishes were applied on the same occasions, on all tooth surfaces. Data were submitted to two-way, repeated-measures ANOVA, Fisher’s LSD test and multivariate linear regression analysis (p<0.05).

Results: Significant increases in mean dmfs were observed at the 3-, 6- and 12-month follow-up examinations, respectively for PLA, F-varnish and F/TMP-varnish. At the end of the follow-up period (12 months), significant differences were observed among all groups, with the lowest dmfs observed for F/TMP-varnish (3.50), followed by F-varnish (3.60) and PLA (3.72). The variables “kindergarten” and “type of varnish” significantly affected caries increment at the end of the 12-month trial, with no significant influence of “gender”, “age” and “baseline dmfs” on this parameter.

Conclusions: The results indicate that clinical efficacy of F/TMP-varnish is superior to that observed for the F-varnish in the primary dentition.

Student Presenter

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: São Paulo State University holds a patent request for a product tested in the study by the National Institute of Industrial Property - INPI/SP, Brazil (C10801811-1 E2), published on April 12, 2011.

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