Title: 0805 - Silver Diamine Fluoride at Lower Concentration to Arrest Dental Decay: A Randomized Controlled Trial
Rodolfo Sinésio Abreu (Presenter)
University of Pernambuco
Arnoldo Filho, University of Pernambuco
Manuela Arnaud, University of Pernambuco
Monica Heimer, University of Pernambuco
Mabel Machado, University of Pernambuco
Aronita Rosenblatt, University of Pernambuco
Objectives: Test the hypothesis that 12% SDF is more effective than 5% fluoride varnish (FV) in arresting and preventing caries.
Methods: A randomized controlled trial comprising 227 six-year-old schoolchildren with untreated decay in the deciduous teeth. 120 individuals received 12% SDF (Cariestop®, Biodinâmica), and 107 received 5% FV (Duraflora®, Medicom). DMFT compared caries arrest and incidence at baseline, 6 and 12 months. Chi-square, Fisher exact test, McNemar, t-test, F test, ANOVA and Bonferroni were used.
Results: At baseline, DMFT indexes were 5.66 ± 3.62 for the SDF group and 5.42 ± 3.4 for the FV group (p = 0.628). SDF was significantly more effective than FV (p < 0.001), and the average numbers of arrested caries after 6 and 12 months were 2.17 ± 1.78 (preventive fraction= 46%; number needed to treat= 1) and 1.62 ± 1.48 (PF = 44%, NNT = 1), respectively. Neither group exhibited caries halt in the permanent dentition.
Conclusions: The results suggested that 12% SDF, applied annually, is more effective in arresting caries in deciduous teeth than 5% FV. No significant difference in the incidence of caries in permanent dentition was showed.
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: NONE