Title: 0792 - A National Study on the Use of Opioid Analgesics in Dentistry


PatrĂ­cia Lino, Universidade Federal de Minas Gerais
Woosung Sohn, Boston University
Astha Singhal, Boston University
Maria Martins, Universidade Federal de Minas Gerais
Maria Elisa Silva, Universidade Federal de Minas Gerais
Mauro Henrique de Abreu (Presenter)
Universidade Federal de Minas Gerais


Objectives: We aimed to describe the opioid prescribing by Brazilian dentists and to compare the regional differences with socioeconomic and health services factors.

Methods: A cross-sectional study was conducted using secondary data on opioid prescribed in dentistry. All prescriptions for opioids written by dentists in 2012 were extracted from the database of the National Controlled Substances Management System, regulated by the Brazilian Health Surveillance Agency. The number of defined daily doses (DDDs) for each prescribed opioid and DDDs per 1000 inhabitant per day for each Brazilian state were calculated. Spearman's rho correlation coefficient was used to identify socioeconomic and health services factors associated with DDD values. Data analysis was performed using IBM SPSS version 25.0.

Results: A total of 141,161 prescriptions for opioids analgesics were recorded which corresponds to 658,855 doses of opioids. Codeine with paracetamol n=117,493 (83.2%) and tramadol n=13,562 (9.6%) were the most commonly dispensed drugs. The national DDDs per 1000 inhabitants per day was 0.0093 (ranging in the Brazilian states from 0.0002 to 0.0216). A moderate correlation was found between the DDDs per 1000 inhabitants per day and proportion of population living in poverty (rs = - 0.624; P < 0.001), visit to the dentist in the last 12 months rs = 0.630; P < 0.001), rate of pharmaceutical establishments (rs = 0.505; P < 0.05).

Conclusions: The prescriptions of opioid analgesics dispensed in clinical practice were low and there were differences among the Brazilian states. These differences were associated with socioeconomic and health services factors.

This abstract is based on research that was funded entirely or partially by an outside source:

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None