Title: 0387 - The Efficacy of Oral Appliance Therapy in Adults With Sleep-disordered Breathing: A Logic Model Framework


Thikriat Al-Jewair (Presenter)
University at Buffalo


Objectives: The use of logic models to improve the understanding of complex interventions beyond the traditional systematic review approach is scarce and has not been fully explored. This study aims to synthesize a logic model on the efficacy of oral appliance Therapy (OAT) in adults with sleep-disordered breathing (SDB).

Methods: A logic model was developed using six high-quality Systematic Reviews (SRs) and Meta-Analyses (MAs) that evaluated the effects of OAT in adults diagnosed with SDB of any severity. The model displayed the short-, intermediate, and long-term outcomes of OAT as well as the impact of these outcomes on the society as a whole based on previous studies and findings. The model took into consideration previous assumptions and external factors.

Results: The short-term outcomes of OAT in comparison to placebo or no intervention included a reduction in the AHI/RDI, ESS, SBP, DBP, Arousal index, and minimum oxygen saturation. The long-term outcomes involved an improvement in health-related quality of life (vitality, contentment, and sleep) and functional outcomes of sleep questionnaire. The impact of these outcomes was an improvement in life expectancy and a reduction in costs per case but a rise in total costs on healthcare system due to increased recognition and treatment.

Conclusions: The OAT Logic model is capable of supplementing research synthesis and providing important information to stakeholders and decision-makers about OAT.

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None