Title: 2819 - Integration of Oral Health Care in ESRD Patients


Ryan Campbell, University of Connecticut
Victoria Barany Nunez, University of Connecticut
Geraldine Weinstein, University of Connecticut
Megyn Clement, University of Connecticut School of Dental Medicine
Ruchir Trivedi, University of Connecticut Health Center
Effie Ioannidou (Presenter)
University of Connecticut


Objectives: End-stage renal disease (ESRD) is characterized by reduced kidney function requiring renal replacement therapy (dialysis or renal transplantation). The prevalence of periodontal disease is significantly higher in ESRD subjects when compared to non-ESRD populations. As ESRD is a state marked with increased inflammatory and oxidative stress burden with implications in cardiovascular mortality, un-treated periodontal disease may be a contributor to such morbidity. The goal of this study is to assess the feasibility of an integrated oral health model in a dialysis settings.

Methods: At the UCONN Health School of Dental Medicine, the relationships of ESRD and periodontal disease are being investigated (IRB # 16-111-1). In this study, clinical oral health outcomes and patient compliance in ESRD subjects are assessed. ESRD subjects in the UCONN dialysis unit with diagnosed, un-treated chronic periodontal disease were randomly assigned to a treatment or control arm. All participants received an initial periodontal examination (quantitative measure) and Oral Health Impact profile (OHIP-14) survey (qualitative measure). Initial intervention included oral hygiene instruction, scaling and root planing. Test subjects received supportive periodontal therapy at 2 and 4 months, while the control subjects received no additional maintenance therapy within the first 6-months.

Results: The majority of patients enrolled thus far are mostly male, non-Hispanic. Seventy three percent of patients enrolled report Black, Multiracial and Asian background. The patients ages ranged from 20-70 years old. Oral exams diagnosed all of the patients with Periodontitis and over half of the patients requiring additional dental care. Only 20% of our patients self-reported no problems with their oral health. We expect to find that the integrated patient care model would produce differences in clinical outcomes when compared to no maintenance therapy.

Conclusions: This study aims to tailor and integrate oral health care model into the daily care of ESRD patients in the dialysis setting.

This abstract is based on research that was funded entirely or partially by an outside source:
National Institutes of Health/ National Institute of Diabetes and Digestive and Kidney Diseases Grant# 1 R21 DK108076-01A1

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None