Title: 0362 - Evaluating the Antibacterial Effect of Silver Layering on Ti Surface


Istvan Lampe (Presenter)
University of Debrecen, Faculty of Dentistry

Zsuzsanna Dombradi, University of Debrecen, Faculty of Medicine
Istvan Csarnovits, University of Debrecen, Faculty of Science and Technology
Peter Hajdu, Hungarian Academy of Sciences Institute for Nuclear Research
Csaba Hegedus, University of Debrecen, Faculty of Dentistry


Objectives: Using osseointegrated dental implants to restore lost dentition has become widely accepted. As the number of placed implants has dramatically increased during the last years it also has been recognised that certain inflammatory complications may occur at a high percentage of the cases. Peri-implant mucositis is diagnosed in more than 50% of patients with implants, peri-implantitis varied between 28-56%. Titanium itself does not have any anti inflammatory feature, but layering silver on the surface could help in preventing the abovementioned inflammation. Our objective was to investigate the antibacterial effect of silver layer on titanium surface either in a simple layer or in nanoparticle form.

Methods: 10x10 mm Grade 2 Titanium plates were used for the investigation. After polishing the plates to mirror like finish three groups were created, Gr1: native titanium surface, Gr2: simple layer formation of silver on Ti surface by Ag Physical Vapour Deposition (PVD), Gr3: formation of silver nanoparticles on Ti surface by annealing the silver layer placed by PVD. Antibacterial efficiency was measured by incubation of Staphylococcus Aureus (ATCC 29213) for 8 hours on each type of surface. The antibacterial effect was formulated to terms of percentage to ease the comparison of the effect. Standard 10 x 10 mm sized microscopic glasses was used as control surface.

Results: Titanium surface had practically no effect on bacterial growth compared to the control surface. Simple silver layered and silver nanoparticles covered surfaces had significant antibacterial effect, 54% and 70% respectively (p<0.01).

Conclusions: Silver covered layers on titanium surfaces demonstrate significant antibacterial effect, that can help in the prevention of development of peri-implant inflammations.

This abstract is based on research that was funded entirely or partially by an outside source:
The work is supported by the GINOP-2.3.2-15-2016-00011 and GINOP-2.3.2-15-2016-00022 projects. The projects are co-financed by the European Union and the European Regonal Development Fund.

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: NONE