Title: 0359 - Effects of Porous Layer on Immediate and Delayed Implant Placements
Do-Gyoon Kim (Presenter)
Ohio State University
Cong Fu, Zimmer Biomet
Elnaz Ajami, Zimmer Biomet
Hai Bo Wen, Zimmer Biomet
Objectives: This study examined whether a porous engineered layer on dental implants can help interfacial bone mineralization during post-implantation healing periods. Nanoindentation based mechanical moduli were assessed to compare the progress of new bone mineralization between the delayed and immediate implant placements.
Methods: Following IACUC approval, trabecular metal™ (TM) dental implants that consist of titanium (Ti) thread and tantalum (Ta) porous layer were placed in 5 dogs following post-extraction healing period of 3 months (delayed placement) and 8 dogs immediately following premolar extraction (immediate placement). The implants were harvested and dissected for nanoindentation at 2, 4, 8, and 12 weeks of post-implantation healing periods. Nanoindentation elastic modulus (E) that is associated with bone tissue mineralization was measured at 3 locations including 1) within the Ti; 2) less than 0.35 mm from the Ta surface (onTa); 3) deeper than 0.35 mm from the Ta surface (inTa). Two way ANOVA was performed to examine the regional variation of E at each healing period (significance, p<0.05).
Results: For the implants with delayed placement (n=1814 indentations), onTa region had significantly higher E values than Ti region for all post-implantation healing periods (p<0.027) while inTa region had significantly higher E values than Ti region at 4 and 8 weeks (p<0.006), and no differences were observed at 2 and 12 weeks (p>0.15). For the implants with immediate placement (n= 2320 indentations), onTa region had comparable E values with Ti region for all post-implantation healing periods (p>0.393) while inTa region showed significantly lower E values than Ti region up to 8 weeks (p<0.025) and no differences were observed at 12 weeks (p=0.064).
Conclusions: The Ta porous engineered layer had comparable or better interface bone quality than the Ti region, which can enhance long-term implant stability for both delayed and immediate implantation protocols.
This abstract is based on research that was funded entirely or partially by an outside source:
Dental Non-Clinical Research, Zimmer Biomet
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: This project is supported by Zimmer Biomet. The co-authors of this abstract including Cong Fu,, Elnaz Ajami, Hai Bo Wen are employee of Zimmer Biomet.