Title: 0601 - Longitudinal Study on Risk Factors for Bone Resorption Around Implants


Tomoaki Mameno (Presenter)
Osaka University Graduate School of Dentistry

Masahiro Wada, Osaka University Graduate School of Dentistry
Yoshinobu Maeda, Osaka University Graduate School of Dentistry
Kazunori Ikebe, Osaka University Graduate School of Dentistry


Objectives: One of the critical complications in implant treatment is peri-implantitis which demonstrate inflammation around mucosa in combination with bone resorption. Many studies showed the correlation between history of periodontitis, smoking and peri-implantitis developing. However, there are few focus on its correlation with prosthetic design. This study aims to identify potential risk factors associated with bone resorption around implants in 3 years longitudinal study.

Methods: Patients were collected from one university hospital and 6 general dental office. Demographic data and treatment histories were collected. In radiographic examination, bone resorption was calculated by comparison of baseline (1 year after prosthesis setting) and follow-up (over 3 years from baseline) dental X-rays.
Generalized estimating equation (GEE) was used to predict bone resorption based on age, gender, history/presence of periodontitis, plaque control record (PCR), parafunctional habits, smoking, drinking, systemic diseases, Eichner classification, fixation methods, connection type, implant diameter/length, prosthetic design, implant location, with/without guided bone regeneration, follow-up period. Statistical significance was set at p-values <0.05.

Results: 448 patients (165 males, 283 females, mean age of 65.8 (95% confidence interval (CI): 65.3-66.3) years) treated with 1352 implants were recruited. Mean bone resorption was 0.26 (95% CI: 0.22-0.29) mm, mean follow-up period was 5.8 (95% CI: 5.69-5.94) years.
The presence of periodontitis (B=0.23, 95% CI: 0.08-0.38, p<0.01), PCR >20% (B=0.11, 95% CI: 0.001-0.214, p=0.047), cement-retained superstructure (B=0.19, 95% CI: 0.07-0.31, p<0.01), external connection (B=0.12, 95% CI: 0.01-0.23, p=0.04), splinting of superstructure (B=0.15, 95% CI: 0.02-0.27, p=0.02), follow-up period (B=0.03, 95% CI: 0.01-0.05, p<0.01), Eichner class C (B=0.26, 95% CI: 0.02-0.51, p=0.03) were positively associated with the bone resorption.

Conclusions: These results suggest that presence of periodontal disease, poor oral hygiene, prothetic design, loss of occlusal supports and function time should be considered as risk factors for bone resorption.

Student Presenter

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: NONE