Title: 0580 - Radio-Density Change After ICON and Brm-ICON Infiltration in Artificial WSL


Ferranti Wong (Presenter)
Queen Mary University of London

Malihe Moeinian, Queen Mary University of London
Graham Davis, Queen Mary University of London
David Mills, Queen Mary University of London
Robert Hill, Queen Mary University of London


Objectives: To measure and compare the radio-density changes in artificial demineralised lesions after infiltration by ICON and a novel Bromine Methacrylate (BrM-ICON) resin.

Methods: Six non-carious premolars were painted with nail-varnish leaving a window of 2x2 mm2 in each side of the enamel surface (n=24). The teeth were immersed in 0.1M acetic acid at pH4.5 for 60 hours to create artificial white spot lesions. For each tooth, an initial X-ray Micr-tomography (XMT) scan was taken using a MuCAT2 scanner. ICON resin was used to infiltrate 2 WSLs according to the manufacturer’s instruction. The other 2 WSLs were infiltrated with BrM and ICON mixtures at 30:70 vol% respectively. A final XMT can was then taken. After alignment, for each lesion, 3 line profiles for each10th XMT slice were used to measure the linear attenuation coefficient (LAC) of the lesion, before and after infiltration. The mean differences between pre- and post-infiltrations were then calculated. It was regarded as statistical different if p is less than 0.5 using t-test.

Results: After infiltrating the LAC was decrease by 0.072 cm-1 (sd=0.1) for ICON, and 0.017 cm-1 (s.d.=0.11) for BrM-ICON. The difference of decrease was significant (p<0.0001) for ICON but not for BrM-ICON. It was found that the decrease of LAC was significantly higher for ICON comparing to the BrM-ICON resin (p<0.0001).

Conclusions: The ICON infiltration technique could further remove mineral in demineralised lesions and reduce radio-density after infiltration. This is probably due to the HCl application. The 30%BrM-ICON mixture can restore the radio-density to the original.

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: NONE