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Title: 0220 - TMP Enhances the Protective Effect of F-varnishes Against Initial Erosion

Authors:

Juliano Pessan (Presenter)
School of Dentistry, Araçatuba, São Paulo State University (UNESP)

Liliana Carolina Báez Quintero, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Mariana Nagata, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Marcelle Danelon, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Diego Felipe Gonçalves, School of Dentistry, Araçatuba, São Paulo State University (UNESP)
Daniela Aguiar, Federal University of Alfenas (UNIFAL-MG)
Vivien Sakai, Federal University of Alfenas (UNIFAL-MG)
Daniela Rios, University of São Paulo
Alberto Delbem, School of Dentistry, Araçatuba, São Paulo State University (UNESP)

Abstract:

Objectives: This study assessed the protective effect of fluoridated varnishes supplemented with micrometric or nanosized sodium trimetaphosphate (TMPmicro or TMPnano, respectively) on initial enamel erosion.

Methods: Bovine enamel blocks were selected by surface hardness (SH) and randomly assigned (n=8/group) into the groups: Placebo (no F/TMP), 5% NaF, 5% NaF+5%TMPmicro, 5% NaF+2.5%TMPnano and 5% NaF+5%TMPnano. Blocks received a single application of the varnishes and were immersed in artificial saliva for 6 h, being gently removed afterwards using a blade and acetone. The blocks were then subjected to four individual erosive challenges (1-min each, 0.75% citric acid, pH=3.5, under agitation at room temperature); SH was determined after each challenge using the same parameters adopted initial SH. Data were analyzed by two-way, repeated measures ANOVA and Student-Newman-Keuls’ test (p<0.05).

Results: Significant differences were observed among the varnishes (p<0.001), times of exposure to acid (p<0.001), and for the interaction between these variables (p<0.001). At 1-min of exposure to acid, the highest surface hardness change was observed for Placebo, followed by 5% NaF and the TMP-containing varnishes (p<0.05), without differences among the latter regardless of the type of particle (micro or nano) or TMP concentration (2.5 or 5%). At 2-, 3-and 4-min, significant differences were observed among Placebo, 5% NaF, 5% NaF/5% TMPmicro and both varnishes containing TMPnano, however, without significant differences between 2.5% and 5% TMPnano.

Conclusions: It was concluded that TMP increases the protective effect of fluoridated varnishes against erosive challenges, with an additional benefit from the use of TMPnano.

This abstract is based on research that was funded entirely or partially by an outside source:
CAPES (PROCAD 2013, grant #88881.068437/2014-01)

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: None.

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