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Description

Title: 0576 - Fluoride Varnish for Childsmile Nursery School Attenders: Randomised Controlled Trial

Authors:

Alex McMahon (Presenter)
University of Glasgow Dental School

William Wright, University of Glasgow Dental School
Turner Steve, University of Glasgow Dental School
David Conway, University of Glasgow Dental School
Lorna Macpherson, University of Glasgow Dental School

Abstract:

Objectives: Studies suggest that fluoride varnish application can reduce caries in both adult and child populations. Childsmile delivers daily toothbrushing in nursery schools and distributes free dental packs of fluoride toothpaste and toothbrushes. This trial aimed to explore the effectiveness and cost-effectiveness of additional preventive fluoride varnish application plus Childsmile treatment as usual (FV), compared to treatment as usual alone (TAU).

Methods: The eligible population for this study was children in the first year of nursery education (Aged 3), either with or without existing caries, with no history of hospitalisation for allergies or asthma and no hypersensitivity to colophony. Children were randomised to either FV or TAU and followed up for two years until the first year of primary education. Treatments were administered at six monthly intervals.
The primary endpoint was ‘worsening of d3mft’ from baseline to 24 months, and the secondary endpoint was worsening of d3t.

Results: A total of 1303 children were randomised, leading to 1150 evaluable children (577 FV, 573 TAU, 12% dropouts). The children were aged mean 3.5 years, 52% female (n=533), 17% with existing caries at baseline (n=195), with near perfect balance between with the groups. Most children received three or four treatments (n=298+680, 85%). Overall 26.9% (n=155) had worsened d3mft in the FV group, and 31.6% (n=181) in the TAU group, with an odds-ratio (OR) of 0.80 (0.62, 1.03), p=0.078. This became significant when adjusted by age, sex, deprivation and prior caries, OR=0.74 (0.55, 0.99), p=0.045. The unadjusted results for worsening of d3t were 0.75 (0.57, 0.99), p=0.043, and when adjusted, OR=0.69 (0.51, 0.94), p=0.017.

Conclusions: There was a modest reduction in the worsening of d3mft in the FV group. This was significant after adjustment, and before and after adjustment for the main secondary endpoint of d3t.

This abstract is based on research that was funded entirely or partially by an outside source:
Scottish Government

Disclosure Statement:
The submitter must disclose the names of the organizations with which any author have a relationship, the nature of the relationship, and the clinical or research area involved. The following is submitted: NONE

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