CE Hours: 1.5

Seq# 15 - Role of Kinases in Etiology and Treatment of Orofacial Pain

This session will be recorded and available through IADR CE On Demand after the meeting for Continuing Education Credit.  

Orofacial pain disorders are highly prevalent conditions in the general population. Because of the important differences in pathophysiology and effective modes of treatment of spinal pain and orofacial pain, it is important to delineate underlying mechanisms of orofacial pain to develop novel drug targets. Cumulative evidence indicates that kinases play important role in pathology-specific activation and sensitization of nociceptive neurons in peripheral and central nervous system. The understanding of the causative pathophysiological and molecular mechanisms for their roles in pain signaling will be critical to develop approaches to identify new class of analgesics that can effectively modulate kinase activities and associated painful conditions.

Learning Objectives:

  • Attendees will appreciate the prevalence of orofacial pain disorders and understand the pathophysiology of these disorders
  • Attendees will be able to recognize that important roles of kinases in pain signaling and their potential as drug targets to develop new class of analgesics.
  • At the end of the symposium, attendees will appreciate the importance of the management of orofacial pain disorders and their clinical and translational perspective.